The basic procedure consists of 3 steps
How to use FUJI DRI-CHEM system
The system is very easy to use. It is designed to be used not only by professional clinical chemistry operators but also by busy doctors and nurses.
1. Pass the QC card through the QC card reader whenever you use slides from a new lot number.
2. Set slides on FUJI DRI-CHEM analyser.
3. Set a sample tube and an Auto TIP in the specified sample rack.
4. Input a sequence No. and a sample ID if necessary.
5. Press the "START" key to initiate testing.
6. The results are printed out to the printer.
7. For details of operation procedure, consult "Instruction Manual " for FUJI DRI-CHEM analyser.
The FDC NX500 automates various time-consuming dilution procedures done by hand such as pipetting and mixing.
Dilutes automatically to a preset dilution ratio by merely setting the dilution cup and dilution solution.
Easy input of patient data
Presentation of results with qick indication
Help menu for assistance in test procedure and maintenance
Multi-functional; many blood components can be tested.
Equipped with electrolyte measuring function.
QC card system
Calibration of each lot can be performed easily by reading the QC card. QC information is memorised for up to two lots. Slide lot differentiation is conducted automatically.
Automates the time-consuming dilution procedure
Completely automated, from pushing the START key to the printout of the data.
There is no need to specify the tests beforehand since two lots of dots on the back of the slide can be read automatically to obtain accurate results.
No pretreatment of sample required
Plasma Filter (PF) can generate a plasma sample by gentle aspirating and separating whole blood in primary tubes within 1 minute.
Just set PF on top of the sample tube and press START
Highly stable slides using excellent chemical technology developed by Fujifilm.
Excellent reproducibility of results, minimal fluctuation throughout the day and no data measurement differences due to different operators.
Operation is quick and so requires less time to acquire test results.
TAT (Turn around time): Time required for 12 tests: ca. 9min.
*TAT is the time from when slides are set until final results
FUJI DRI-CHEM AUTO TIPS are newly designed to achieve higher mixing speed, resulting in more stable and reliable results.
|Classification||Parameter||Measurement range Unit (A)||Measurement range Unit (B)||Measurement time (min.)|
|Biochemical tests (Enzymes)||ALP||50-3500 U/L||0.84-58.45 µkat/L||4|
|AMYL||10-1800 U/L||0.17-30.06 µkat/L||5|
|CHE||5-500 U/L||0.08-8.35 µkat/L||4.5|
|CKMB||1-300 U/L||0.02-5.01 µkat/L||5|
|CPK||10-2000 U/L||0.17-33.40 µkat/L||4|
|GGT||10-1200 U/L||0.17-20.04 µkat/L||5|
|GOT/AST||10-1000 U/L||0.17-16.70 µkat/L||4|
|GPT/ALT||10-1000 U/L||0.17-16.70 µkat/L||4|
|LAP||10-500 U/L||0.17-8.35 µkat/L||4|
|LDH||50-900 U/L||0.84-15.03 µkat/L||2|
|Biochemical tests (General chemistry)||ALB||1.0-6.0 g/dL||10-60 g/L||6|
|BUN||5.0-140.0 mg/dL||1.79-49.98 mmol/L||4|
|Ca||4.0-16.0 mg/dL||1.00-4.00 mmol/L||4|
|CRE||0.2-24.0 mg/dL||18-2122 µmol/L||5|
|DBIL||0.1-16.0 mg/dL||2-274 µmol/L||5|
|GLU||10-600 mg/dL||0.6-33.3 mmol/L||6|
|HDL-C||10-110 mg/dL||0.26-2.84 mmol/L||6|
|IP||0.5-15.0 mg/dL||0.16-4.84 mmol/L||5|
|Mg||0.2-7.0 mg/dL||0.08-2.88 mmol/L||4.5|
|NH3||10-500 µg/dL||7-357 µmol/L||2|
|TBIL||0.2-30.0 mg/dL||3-513 µmol/L||6|
|TCHO||50-450 mg/dL||1.29-11.64 mmol/L||6|
|TCO2||5-40 ´mmol/L||5-40 mmol/L||5|
|TG||10-500 mg/dL||0.11-5.65 mmol/L||4|
|TP||2.0-11.0 g/dL||20-110 g/L||6|
|UA||0.5-18.0 mg/dL||30-1071 µmol/L||4|
|Biochemical tests (Electrolytes)||Na||75-250 mEq/L||75-250 mmol/L||1|
|K||1.0-14.0 mEq/L||1.0-14.0 mmol/L|
|Cl||50-175 mEq/L||50-175 mmol/L|
|Immunological test||CRP||0.3-7.0 mEq/L||3-70 mg/L||5|
|Measurement tests||Colorimetry: 28 tests Electrolytes: 3 tests|
|Throughput||Colorimetry: 120 tests/hour Combined Electrolite/Colorimetry:128 tests/hour|
|TAT (Turn around time)||Time required for 12 tests: ca 9min. *TAT is the time from when slides are set until final results.|
|Number of sample racks||1|
|Number of incubations||Colorimetry: 12, Electrolytes: 1|
|Measurement time||Colorimetry: 2 to 6 minutes/test, Electrolytes: 1 minute/ 3 tests (Na-K-Cl)|
|Sample types||Plasma, Serum, Whole blood (with Plasma Filter)|
|Sample volume||Colorimetry: 10 µL/ test, Electrolytes: 50 µL/ 3 tests (Na-K-Cl)|
|Data transmission to PC||LAN or RS-232C serial|
|Data printing||Thermal printer|
|Electrical requirements||AC 100-240V, 50/60 Hz, 200VA|
|Dimensions||470 (W) x 360 (D) x 420 (H)mm|
|Weight||Approx. 25 kg|
|Operating temperature||15 to 32 °C|
|Operating humidity||30 to 80 %RH|
The FUJI DRI-CHEM (FDC) system based on a multilayered film method was first announced in 1980.
The initial product was a dry chemistry slide and an analyzer for measuring glucose concentration by spotting a 6-microliter sample of whole blood. The slide had a special spreading layer made of cloth, which enabled the use of whole blood samples.
Since then, various DRI-CHEM slides and analyzers have been developed to fulfill the increasing needs of emergency testing, and a range of peripheral items were also developed. For instance, special pipette tips, now called FUJI CLEAN TIPS, were introduced to enable automatic spotting. Because the tips don't require wiping, there is little danger of operator contamination from blood samples.
The recently introduced FDC series are now widely used in international markets as automatic clinical chemistry systems. The FUJI DRI-CHEM system is used not only in clinical laboratories but also in veterinary clinics.
The system has two major principles of measurement, one is colorimetric and the other is potentiometric.
For a glucose slide, the actual measurement is conducted as follows. 10 microliters of plasma or serum are spotted on a FUJI DRI-CHEM SLIDE GLU-PIII. After spotting, the sample spreads uniformly on the spreading layer and diffuses into the underlying layer. As the process proceeds, large molecular weight components such as proteins or dye components are filtrated, and only small molecular weight components are able to permeate and diffuse into the reagent layer. Glucoseoxidase (GOD) catalyzes the oxidization of sample glucose to generate hydrogen peroxide. In the presence of peroxidase (POD), hydrogen peroxide reacts with dye precursors and finally forms red dye. The slide is incubated at 37°C for a specified number of minutes in the FUJI DRI-CHEM analyzer and the optical reflection density is measured at 505nm. The aforementioned optical reflection density is then converted into the glucose concentration using a calibration curve preinstalled in the analyzer.
Potentiometric analysis is based on measurement of the generated voltage difference between ion selective electrodes applied to a reference solution and to the sample. In the FUJI DRI-CHEM system, ion selective electrodes for sodium (Na), potassium (K) and chloride (Cl) are set into one slide. After spotting 50 microliters of the sample and of the reference solution on the slide, the slide is incubated for one minute in the FUJI DRI-CHEM analyzer and the potentiometric difference between the sample and the reference solution is measured. The potentiometric value is then converted into each electrolyte concentration using a calibration curve preinstalled in the analyzer.