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France

FUJI DRI-CHEM 4000i

The basic procedure consists of 3 steps

Automates various time-consuming dilution procedures done by hand such as pipetting and mixing.
Dilutes automatically to a preset dilution ratio by merely setting the dilution cup and dilution solution.

How to use FUJI DRI-CHEM system

The system is very easy to use. It is designed to be used not only by professional clinical chemistry operators but also by busy doctors and nurses.

  1. Pass the QC card through the QC card reader whenever you use slides from a new lot number.
  2. Set slides on FUJI DRI-CHEM analyser.
  3. Set a sample tube and an Auto TIP in the specified sample rack.
  4. Input a sequence No. and a sample ID if necessary.
  5. Press the "START" key to initiate testing.
  6. The results are printed out to the printer.
    For details of operation procedure, consult "Instruction Manual " for FUJI DRI-CHEM analyser.

Функциональность

Возможность анализа ферментов, общая химии, иммунологии и электролитов. 

Удобная калибровка

Калибровку для каждой партии без труда выполняется путем считывания магнитной карты, которая находится в каждой коробке со слайдами. Считывать карту необходимо при использовании только новых лотов.

Распознавание новых лотов слайдов выполняется автоматически путем считывать штрих-кода на задней стороне слайда.

Автоматизация

Автоматизация различных процедур, занимающих много времени при выполнении вручную, например, дозирования пипеткой и смешивания.

Для автоматического разведения достаточно установить емкость для разведения и раствор для разведения. 

Высокая надежность

Исключительная стабильность слайдов благодаря применению фотопленочной технологии, разработанной компанией FUJIFILM.

Отличная воспроизводимость результатов, минимальные расхождения в течение рабочего дня и отсутствие различий в результатах измерений при работе разных операторов.

Parameters

Classification Parameter Measurement range Unit (A) Measurement range Unit (B) Measurement time (min.)
Biochemical tests (Enzymes) ALP 50-3500 U/L 0.84-58.45 µkat/L 4
AMYL 10-1800 U/L 0.17-30.06 µkat/L 5
CHE 5-500 U/L 0.08-8.35 µkat/L 4.5
CKMB 1-300 U/L 0.02-5.01 µkat/L 5
CPK 10-2000 U/L 0.17-33.40 µkat/L 4
GGT 10-1200 U/L 0.17-20.04 µkat/L 5
GOT/AST 10-1000 U/L 0.17-16.70 µkat/L 4
GPT/ALT 10-1000 U/L 0.17-16.70 µkat/L 4
LAP 10-500 U/L 0.17-8.35 µkat/L 4
LDH 50-900 U/L 0.84-15.03 µkat/L 2
Biochemical tests (General chemistry) ALB 1.0-6.0 g/dL 10-60 g/L 6
BUN 5.0-140.0 mg/dL 1.79-49.98 mmol/L 4
Ca 4.0-16.0 mg/dL 1.00-4.00 mmol/L 4
CRE 0.2-24.0 mg/dL 18-2122 µmol/L 5
DBIL 0.1-16.0 mg/dL 2-274 µmol/L 5
GLU 10-600 mg/dL 0.6-33.3 mmol/L 6
HDL-C 10-110 mg/dL 0.26-2.84 mmol/L 6
IP 0.5-15.0 mg/dL 0.16-4.84 mmol/L 5
Mg 0.2-7.0 mg/dL 0.08-2.88 mmol/L 4.5
NH3 10-500 µg/dL 7-357 µmol/L 2
TBIL 0.2-30.0 mg/dL 3-513 µmol/L 6
TCHO 50-450 mg/dL 1.29-11.64 mmol/L 6
TG 10-500 mg/dL 0.11-5.65 mmol/L 4
TP 2.0-11.0 g/dL 20-110 g/L 6
UA 0.5-18.0 mg/dL 30-1071 µmol/L 4
Biochemical tests (Electrolytes) Na 75-250 mEq/L 75-250 mmol/L 1
K 1.0-14.0 mEq/L 1.0-14.0 mmol/L
Cl 50-175 mEq/L 50-175 mmol/L
Immunological test CRP 0.3-7.0 mEq/L 3-70 mg/L 5

Main specifications for FUJI DRI-CHEM 4000i

Measurement tests Colorimetry: 26 tests Electrolytes: 3 tests
Throughput Colorimetry: 60 tests/hour Electrolytes: 140 tests/hour Combined: 77 tests/hour
TAT (Turn around time) Time required for 6 tests: 8min 42sec. Time required for 12 tests: 16min 37sec. *TAT is the time from when slides are set until final results.
Number of sample racks 1
Number of incubations Colorimetry: 6, Electrolytes: 1
Measurement time Colorimetry: 2 to 6 minutes/test, Electrolytes: 1 minute/ 3 tests (Na-K-Cl)
Sample types Plasma, Serum, Whole blood (NH3-W,Na-K-Cl)
Sample volume Colorimetry: 10 µL/ test, Electrolytes: 50 µL/ 3 tests (Na-K-Cl)
Data transmission to PC USB 2.0 or RS-232C serial D-Sub 9 pin -9 pin cross cable
Data printing Thermal printer
Electrical requirements AC 100-240V, 50/60 Hz, 200VA
Dimensions 415 (W) x 390 (D) x 290 (H)mm
Weight Approx. 20 kg
Operating temperature 15 to 32 °C
Operating humidity 30 to 80 %RH

History

The FUJI DRI-CHEM (FDC) system based on a multilayered film method was first announced in 1980.
The initial product was a dry chemistry slide and an analyzer for measuring glucose concentration by spotting a 6-microliter sample of whole blood. The slide had a special spreading layer made of cloth, which enabled the use of whole blood samples.
Since then, various DRI-CHEM slides and analyzers have been developed to fulfill the increasing needs of emergency testing, and a range of peripheral items were also developed. For instance, special pipette tips, now called FUJI CLEAN TIPS, were introduced to enable automatic spotting. Because the tips don't require wiping, there is little danger of operator contamination from blood samples.
The recently introduced FDC series are now widely used in international markets as automatic clinical chemistry systems. The FUJI DRI-CHEM system is used not only in clinical laboratories but also in veterinary clinics.

Principle

The system has two major principles of measurement, one is colorimetric and the other is potentiometric.

Colorimetric slide
(Enzymes, General chemistry, Immunology)

For a glucose slide, the actual measurement is conducted as follows. 10 microliters of plasma or serum are spotted on a FUJI DRI-CHEM SLIDE GLU-PIII. After spotting, the sample spreads uniformly on the spreading layer and diffuses into the underlying layer. As the process proceeds, large molecular weight components such as proteins or dye components are filtrated, and only small molecular weight components are able to permeate and diffuse into the reagent layer. Glucoseoxidase (GOD) catalyzes the oxidization of sample glucose to generate hydrogen peroxide. In the presence of peroxidase (POD), hydrogen peroxide reacts with dye precursors and finally forms red dye. The slide is incubated at 37°C for a specified number of minutes in the FUJI DRI-CHEM analyzer and the optical reflection density is measured at 505nm. The aforementioned optical reflection density is then converted into the glucose concentration using a calibration curve preinstalled in the analyzer.

Parameters

Classification Parameter Measurement range Unit (A) Measurement range Unit (B) Measurement time (min.)
Biochemical tests (Enzymes) ALP 50-3500 U/L 0.84-58.45 µkat/L 4
AMYL 10-1800 U/L 0.17-30.06 µkat/L 5
CHE 5-500 U/L 0.08-8.35 µkat/L 4.5
CKMB 1-300 U/L 0.02-5.01 µkat/L 5
CPK 10-2000 U/L 0.17-33.40 µkat/L 4
GGT 10-1200 U/L 0.17-20.04 µkat/L 5
GOT/AST 10-1000 U/L 0.17-16.70 µkat/L 4
GPT/ALT 10-1000 U/L 0.17-16.70 µkat/L 4
LAP 10-500 U/L 0.17-8.35 µkat/L 4
LDH 50-900 U/L 0.84-15.03 µkat/L 2
Biochemical tests (General chemistry) ALB 1.0-6.0 g/dL 10-60 g/L 6
BUN 5.0-140.0 mg/dL 1.79-49.98 mmol/L 4
Ca 4.0-16.0 mg/dL 1.00-4.00 mmol/L 4
CRE 0.2-24.0 mg/dL 18-2122 µmol/L 5
DBIL 0.1-16.0 mg/dL 2-274 µmol/L 5
GLU 10-600 mg/dL 0.6-33.3 mmol/L 6
HDL-C 10-110 mg/dL 0.26-2.84 mmol/L 6
IP 0.5-15.0 mg/dL 0.16-4.84 mmol/L 5
Mg 0.2-7.0 mg/dL 0.08-2.88 mmol/L 4.5
NH3 10-500 µg/dL 7-357 µmol/L 2
TBIL 0.2-30.0 mg/dL 3-513 µmol/L 6
TCHO 50-450 mg/dL 1.29-11.64 mmol/L 6
TG 10-500 mg/dL 0.11-5.65 mmol/L 4
TP 2.0-11.0 g/dL 20-110 g/L 6
UA 0.5-18.0 mg/dL 30-1071 µmol/L 4
Biochemical tests (Electrolytes) Na 75-250 mEq/L 75-250 mmol/L 1
K 1.0-14.0 mEq/L 1.0-14.0 mmol/L
Cl 50-175 mEq/L 50-175 mmol/L
Immunological test CRP 0.3-7.0 mEq/L 3-70 mg/L 5